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Christophe Dessimoz
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Christophe Dessimoz
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-====== Welcome ====== +{{ :​go_book_cover.jpeg?​direct&​400|}}
 Welcome to the website of the "Gene Ontology Handbook",​ a handbook on the fundamentals of Gene Ontology, its use in gene annotation, and its application in bioinformatic analyses. Welcome to the website of the "Gene Ontology Handbook",​ a handbook on the fundamentals of Gene Ontology, its use in gene annotation, and its application in bioinformatic analyses.
-{{ :​go_book_cover.jpeg?​direct&​400|}} +   * [[Table ​of Contents]] 
-^  PART I: Fundamentals ​ ^^  +   * Download ​the book for free (open access): [[http://​link.springer.com/​content/​pdf/​10.1007%2F978-1-4939-3743-1.pdf|PDF]] [[http://​link.springer.com/​download/​epub/​10.1007/​978-1-4939-3743-1.epub|EPUB]] 
-|Primer on Ontologies|Janna Hastings| +   * Download [[http://​link.springer.com/​book/​10.1007%2F978-1-4939-3743-1|individual chapters]] 
-|The Gene Ontology and the meaning ​of biological function|Paul Thomas| +   * Electronic version of the GO python tutorial (Chapter 16)  
-|Primer on the Gene Ontology|Pascale Gaudet, Nives Skunca, James C Hu and Christophe Dessimoz| +     * [[http://​nbviewer.jupyter.org/​urls/​dessimozlab.github.io/​go-handbook/​GO%20Tutorial%20in%20Python%20-%20Exercises.ipynbwithout solutions]] 
-^  PART IIMaking GO annotations ​ ^^  +     * [[http://​nbviewer.jupyter.org/​urls/​dessimozlab.github.io/​go-handbook/​GO%20Tutorial%20in%20Python%20-%20Solutions.ipynb|with solutions]] ​ 
-|Best practices in manual annotation with the Gene Ontology|Sylvain Poux and Pascale Gaudet+   * Buy a hardcopy
-|Computational methods for annotation transfers from sequence|Domenico Cozzetto and David Jones| +      * [[http://​www.springer.com/​us/​book/​9781493937417|Springer Shop]] (if you have co-authored a chapter in this or any other Springer bookyou are entitled to a [[http://​www.springer.com/​gp/​help/​discounts-for-authors/​510|40% author discount]]) 
-|Text Mining to Support Gene Ontology Curation and Back|Patrick Ruch| +      * Amazon [[https://​www.amazon.com/​Ontology-Handbook-Methods-Molecular-Biology/​dp/​1493937413/ ​.com ]] / [[https://​www.amazon.co.uk/​Ontology-Handbook-Methods-Molecular-Biology/​dp/​1493937413/ ​.co.uk ]] / [[https://​www.amazon.fr/​Ontology-Handbook-Methods-Molecular-Biology/​dp/​1493937413/ ​| .fr ]] / [[https://​www.amazon.de/​Ontology-Handbook-Methods-Molecular-Biology/​dp/​1493937413/ ​.de ]] 
-|How does the scientific community contribute to Gene Ontology?​|Ruth Lovering| + 
-^  PART IIIEvaluating ​GO annotations ​ ^^  +
-|Evaluating computational Gene Ontology annotations|Nives Skunca, Richard JRoberts and Martin Steffen+
-|Evaluating functional annotations of enzymes using the Gene Ontology|Gemma Holliday, Rebecca Davidson, Eyal Akiva and Patricia Babbitt| +
-|Community-Based Evaluation of Computational Function Prediction|Predrag Radivojac and Iddo Friedberg+
-^  PART IVUsing the GO  ^^  +
-|Get GO! Retrieving GO data using AmiGOQuickGO, API, Files, and Tools.|Monica C Munoz-Torres and Seth Carbon+
-|Semantic Similarity in the Gene Ontology|Catia Pesquita| +
-|Gene-Category Analysis|Sebastian Bauer| +
-|Gene OntologyPitfalls, Biases, Remedies|Pascale Gaudet and Christophe Dessimoz| +
-|Visualising GO annotations|Fran Supek and Nives Skunca| +
-|A Gene Ontology ​Tutorial in Python|Alex Warwick Vesztrocy and Christophe Dessimoz| +
-^  PART VAdvanced GO topics ​ ^^  +
-|Annotation Extensions|Rachael Huntley and Ruth Lovering| +
-|The Evidence ​Ontology: Supporting Conclusions & Assertions with Evidence|Marcus Chibucos, Jim Hu, Deborah ASiegele and Michelle Giglio| +
-^  PART VIBeyond the GO  ^^  +
-|Complementary Sources Of Protein Functional Information:​ The Far Side Of GO|Nicholas Furnham| +
-|Integrating bio-ontologies and controlled clinical terminologies:​ from base pairs to bedside phenotypes|Spiros Denaxas+
-^  PART VII: Conclusion ​ ^^  +
-|The vision and challenges of the Gene Ontology|Suzanna E. Lewis|+
 +The book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians,​ it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the //Methods in Molecular Biology// book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, //The Gene Ontology Handbook// serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.